1. mattress work on slatted bed base, aka platform beds. 2. all memory foam mattresses have a smell when first unrolled, mine dissipated after two days. i did not sleep on it the first night, i just let it breathe and expand. 3. i would only think that a thicker layer of memory foam would be more comfy for my preference. note that the memory foam only makes up the top layer of the mattress so the preferred thickness of the memory foam should be something you consider because they are all different. 4. that being said, since i got this mattress, i have not woken up with any backaches. 5. keep in mind that memory foam mattresses are WARMER than traditional inner spring because the foam touches every inch of your body therefore reducing the air circulation around you.