Nmda Receptor Protocols (Paperback)
 

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Nmda Receptor Protocols (Paperback)

Series Volume 128
Today $118.45
Item #: 14988862
    Min Li and a panel of hands-on experimentalists detail state-of-the-art molecular techniques for studying NMDA ligand-gated ion channels and developing assays for nontherapeutic lead selection. The topics range from cDNA cloning to in vitro and in vivo......more

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Min Li and a panel of hands-on experimentalists detail state-of-the-art molecular techniques for studying NMDA ligand-gated ion channels and developing assays for nontherapeutic lead selection. The topics range from cDNA cloning to in vitro and in vivo investigation of the channel complex in the mammalian brain. Additional topics include the biochemical analysis of the channel protein and the construction of various heterologous systems for both basic research and high throughput screens (HTS) for pharmaceutical chemicals. Although the focus is on NMDA receptors, the methods are applicable to other ligand-gated ion channels and with some modification may be extended to related membrane signaling receptors. NMDA Receptor Protocols offers today's scientists powerful methods for basic research on NMDA receptor structure and function, as well as enormous opportunities for clinical investigation toward the development of novel bioactive compounds.

Series Title:
Methods in Molecular Biology
Genre:
MEDICAL / Neuroscience
Audience:
Professional and scholarly
Number Within Series:
128
Format:
Paperback
Pages:
208
Language:
English
Publisher:
Humana Pr Inc
Publish Date:
11/19/2010
Copyright Year:
1999
ISBN:
9781617371462
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