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Fusion Protein Technologies for Biopharmaceuticals: Applications and Challenges (Hardcover)

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ITEM# 14779067
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ITEM#: 14779067

STEFAN R. SCHMIDT, PhD, is Vice President for Downstream Processing at Rentschler Biotechnology. Previously, he served as CSO at ERA Biotech and Associate Director for Protein Science at AstraZeneca. Dr. Schmidt has chaired many international conferences and written several original articles, reviews, and book chapters.

This book presents the state-of-the-art for development of fusion proteins, demonstrates current concepts, describes multiple applications, and discusses typical challenges linked to these molecules. It overviews the multitude of possibilities to design novel protein drugs while balancing between proven concepts and new ideas that have not reached the clinic yet. The book is structured into three larger parts. First general issues and concepts are discussed before in the second part examples on the three categories (time, toxicity, and targeting) are presented. Finally, novel concepts and the rising class of multispecifc antibodies are described. Together, the chapters combine the success stories of marketed drugs with the dynamic preclinical and clinical research into novel drugs addressing unmet medical needs.

Specs

ISBN 9780470646274
Genre MEDICAL / Pharmacology
Format Hardcover
Pages 624
Publisher Date 2013-03-18 00:00:00.0
Publisher John Wiley & Sons Inc
Copyright Year 2013
Height 11.25 in
Wdth 8.75 in
Thickness 2.0 in
Unit weight 3.92 lb
Language English
Subtitle Applications and Challenges
Edition Number 1
Audience Professional and scholarly
Country of Origin United States

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